
Infertility and the Role of Coenzyme Q10

Infertility is often a silent struggle that affects millions of couples worldwide. It is the inability to conceive even after 12 months of regular, unprotected intercourse. Infertility impacts both men and women equally, and with medical interventions like IVF and IUI, which offer hope to many couples, a promising supplement like Coenzyme Q10, with the potential benefits for both male and female fertility.
Understanding Infertility
There are many causes that contribute to infertility, like hormonal imbalances, structural abnormalities, age, lifestyle choices, and underlying medical conditions like polycystic ovary syndrome or endometriosis in women and low sperm count or motility issues in men.
Age is one of the most significant factors. With an increase in the age of women, it affects their egg quality and quantity, particularly after 35. Men, too, experience a change in sperm quality and quantity over a period.
What is Coenzyme Q10?
Coenzyme Q10 (CoQ10), also known as ubiquinone, is a fat-soluble, vitamin-like molecule naturally present in every cellular membrane within our bodies. 1
It is a naturally occurring antioxidant that is found in every cell of the body. The main role is to produce energy within the mitochondria- the powerhouse of our cells. As we age, the levels of CoQ10 decrease, which impairs cellular energy production and increases oxidative stress.
Given the energy-intensive processes involved in both egg and sperm development, CoQ10’s role in reproductive health is significant.
How CoQ10 Supports Female Fertility
1. Improves Egg Quality
As mentioned, with age, the mitochondrial function in the egg declines, leading to an increased risk of chromosomal abnormalities. CoQ10 supports mitochondrial function, which helps to improve egg quality and increases the chances of successful fertilization.
2. Delays Ovarian Aging
Ovarian reserve also diminishes with age. The use of CoQ10 also helps to slow down ovarian aging, which helps to enhance mitochondrial activity and reduce oxidative stress in the ovaries.
3. Supports IVF Outcomes
Many studies have shown that if CoQ10 is taken before IVF treatment, the chances of more eggs being retrieved and having higher embryo quality, which improves the chances of getting pregnant.
How CoQ10 Supports Male Fertility
CoQ10 is equally important for male reproductive health. With oxidative stress, the sperm cells are at higher risk of damage, which impacts the sperm count, motility, and morphology.
1. Enhances Sperm Motility
As motility is the main factor for sperm to reach the egg to be fertilized, it can be beneficial for men's fertility. CoQ10 has a significant role in improving sperm motility.
2. Improves Sperm Count and Morphology
CoQ10 supplements saw an increase in sperm concentration and morphology, as well as motility.
3. Reduces Oxidative Damage
As oxidative stress can damage the DNA within sperm cells, which affects embryo development, CoQ10 is an antioxidant that helps to neutralize free radicals and decrease oxidative stress.
Fertifre M Plus: Empowering Male Fertility Naturally
Infertility is a challenging issue for many couples. In many cases, male factors also contribute to difficulty in conceiving. Fertifre M Plus is a carefully crafted supplement that is designed to support male reproductive health and enhance fertility outcomes.
ANTIOXIDANTS
COENZYME Q10 (COQ10)- An essential cofactor for energy production with major antioxidant properties.2
Has a beneficial effect on seminal quality, especially regarding sperm motility.2
Supports spermatogenesis in idiopathic male infertility.2
AMINO ACIDS
L-CARNITINE L-TARTARATE-
Increases sperm motility, morphology, and maturation while reducing apoptosis.3
Significant improvements in sperm count, concentration, and morphology in patients with idiopathic oligo-astheno-teratozoospermia.3
L-ARGININE- Increases sperm volume, concentration, motility, and morphology by increasing eNOS activity 4
PHYTONUTRIENTS
PANAX KOREAN GINSENG EXT. 20% GINSENGOIDS - An aphrodisiac, used to treat sexual dysfunction as well as to enhance sexual behavior.5
LYCOPENE- Decreases lipid peroxidation and DNA damage and improves sperm count and viability.6
MINERALS
SELENIUM- increases sperm concentration, motility, seminal antioxidant capacity, and reduces Sperm DNA fragmentation (SDF) in patients with idiopathic oligoasthenoteratospermia.7
ZINC- Improves sperm quality with an increase in sperm density, progressive motility, and improved conception and pregnancy outcome.8
What Fertifre M Plus do?
A potent aphrodisiac that supports empirical treatment of male infertility
Supports Spermatogenesis
Reduces Apoptosis
Improved Seminal Quality
Protects Sperm DNA From ROS Damage
Decreases DNA Fragmentation Of The Sperm
Increases Sperm Motility & Morphology
Improves Conception & Pregnancy Outcome
Increases Sperm Count & Concentration
Conclusion
Coenzyme Q10 is a powerful ingredient with promising benefits to prevent infertility for both males and females. Its role in supporting mitochondrial function and reducing oxidative stress has an impact on sperm quality and motility, which is an important factor for successful conception. For men, it impacts the quality of sperm motility, count, and DNA integrity.
Supplements like Fertifre M Plus harness the power of CoQ10 alongside other fertility-supporting ingredients such as amino acids, antioxidants, minerals, and phytonutrients. This formulation addresses multiple aspects of male reproductive health. Its ability to enhance egg and sperm quality makes it a valuable tool for couples trying to conceive naturally.
References
Ref1- https://www.ncbi.nlm.nih.gov/books/NBK531491/
Ref2- Antioxidants (Basel). 2021 Jun; 10(6): 874.
Ref3- Male Infertility: Treasure Island (FL): StatPearls Publishing; 2023 Jan-.
Ref4- Br J Pharmacol. 2015 Mar; 172(6): 1455–1467.
Ref5- Spermatogenesis. 2013 Jul 1; 3(3): e26391.
Ref6- Asian J Androl. 2014 May-Jun; 16(3): 420–425.
Ref7- Biol Trace Elem Res. 2023 Mar 23.
Ref8- J Reprod Infertil. 2018 Apr-Jun; 19(2): 69–81.