Arthritis is used for a group of disease that affects the joints and cause pain, swelling, and stiffness which in severe cases can lead to disability. The condition is generally associated with aging, but it can affect individuals in any age group. In this blog, we will understand the symptoms and treatment options that can help to manage the condition effectively. Types of Arthritis There are three types of arthritis: osteoarthritis (OA), rheumatoid arthritis (RA), Gout, Ankylosing spondylitis, Psoriatic arthritis, and Juvenile arthritis. Osteoarthritis (OA) Osteoarthritis is the most common type of arthritis. It mostly occurs when the protective layer of cartilage, which is at the end of the bone, wears down over time. It mostly affects the older adults. This degeneration leads to pain and decreased joint flexibility. It basically occurs due to wear and tear of cartilage but other factors. Rheumatoid Arthritis (RA) Rheumatoid Arthritis is an autoimmune disorder, which means the body's immune system mistakenly attacks its own tissue. This leads to inflammation which causes pain, stiffness, and long-term joint damage. This condition mainly affects at any age but is more common in women than men. The exact cause is unknown but can be triggered by environmental and genetic factors.

Gout

In this condition, sharp uric acid crystals are formed in the joints. It usually affects the toe and lower limbs.

Ankylosing spondylolysis

In this condition, the inflammation affects the spine causing pain, stiffness, and potential fusion of vertebrae.

Psoriatic arthritis

It is an autoimmune condition that affects the skin and joints causing inflammation, pain, and stiffness. It sometimes accompanies psoriasis leading to swelling and redness. If early diagnosis happens it may prevent severe complications.

Juvenile Arthritis

This condition usually affects kids and teens under 16 and causes joint inflammation, pain, and stiffness. This can affect the growth, mobility, and daily routine of kids.

Managing Arthritis with Boscofre 

Shallaki(Boswellia Serrata)

Boswellia serrata improved physical function and pain due to their anti-arthritis and anti-inflammatory properties.¹

It suppresses bone resorption without inducing cell death and helps to treat bone loss.

Ginger(Zingiber officinale)

It has anti-inflammatory and analgesic properties.²

It involves stimulating an inflammatory response by the decline of cartilage in joints leading to pain, stiffness, and decreased movement of joints.³

It inhibits osteoclastogenesis & stimulates the differentiation of osteoblasts.

HADJOD(Cissus Quadrangularis Extract)

Exhibiting osteoprotective potential in various bone diseases, especially osteoporosis and fractures.

Osteoprotective and immunoporotic (the osteoprotective potential of Cissus Quadrangularis via modulating the host immune system) potential of Cissus Quadrangularis in preventing inflammatory bone loss under oestrogen-deficient conditions.⁴ It is used for bone healing.⁵

Cissus quadrangularis exhibits strong antioxidant and free radical scavenging activity.⁶

Tumeric(Curcuma Long Root Powder)

It has anti-inflammatory properties which help alleviate joint swelling and stiffness.

Suppresses osteoclast differentiation by scanverging the generated intracellular reactive oxygen spicies(ROS) & inhibits osteoclast bone resorption & stimulates apoptosis.

Piperine

Piperine has anti-inflammatory, antinociceptive, and anti arthritic effects.⁷

Plays crucial role in reducing both the propagation of inflammation and joint damage.⁸

Natural Amino Sugar

Glucosamine

It improves the symptoms and delays the structural progression of osteoarthritis.⁹

The mechanisms of action for glucosamine include maintaining elasticity, strength and resilience of the cartilage.¹⁰

Protein

Collagen Peptides Type1

This specifically is a major component of joint cartilage. The supplement helps to improve joint health, reduce pain and increase mobility.

Collagen Peptide supplementation can stimulate cartilage production, reduce pain, and improve joint function in individuals with osteoarthritis.¹¹

Methylsulfonylmethane (MSM) It is widely known for its anti-inflammatory and analgesic properties. It plays a key role in the formation of connective tissues, which include cartilage, tendons, and ligaments. Helps to improve joint health by reducing pain and inflammation. It has also been found to improve joint flexibility and function, contributing to the overall reduction of arthritis symptoms.¹²

Conclusion Arthritis can be a challenging condition to manage, with the pain, stiffness, and reduced mobility it can affect keeping up with day-to-day routine. This makes it important to find a solution that can help manage the symptoms of arthritis. Boscofre by Fredun Nutrition offers a natural and holistic solution that consists of ingredients like Phytonutrients- Boswellia Serrata, Zingiber officinale, Piperine, Natural Amino Sugar like Glucosamine, Protein like Collagen Peptides Type 1 and Methyl Sulphonyl Methane. This helps to maintain good joint health by preventing pain, stiffness, inflammation and improve mobility. Take the first step toward better joint health with Boscofre—your ally in the fight against arthritis. 

References

Ref1- Kimmatkar N., Thawani V., Hingorani L., Khiyani R. Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee—A randomized double blind placebo controlled trial. Phytomedicine. 2003;10:3–7. doi: 10.1078/094471103321648593.

Ref2- Tripathi S., Maier K., Bruch D., Kittur D. Ginger and Its Active Ingredient 6-Gingerol down Regulate pro-Inflammatory Cytokine Release by Macrophages. J. Surg. Res. 2006;130:318. doi: 10.1016/j.jss.2005.11.456.

Ref3- Bolognesi, G.; Belcaro, G.; Feragalli, B.; Cornelli, U.; Cotellese, R.; Hu, S.; Dugall, M. Movardol®(n-Acetylglucosamine, Boswellia Serrata, Ginger) Supplementation in the Management of Knee Osteoarthritis: Preliminary Results from a 6-Month Registry Study. Eu.R Rev. Med. Pharmacol. Sci. 2016, 20(24), 5198–5204.

Ref4- Ref1- Azam, Z.; Sapra, L.; Baghel, K.; Sinha, N.; Gupta, R.K.; Soni, V.; Saini, C.; Mishra, P.K.; Srivastava, R.K. Cissus quadrangularis (Hadjod) Inhibits RANKL-Induced Osteoclastogenesis and Augments Bone Health in an Estrogen-Deficient Preclinical Model of Osteoporosis Via Modulating the Host Osteoimmune System. Cells 2023, 12, 216. https://doi.org/10.3390/cells12020216

Ref5- Ref- Reddy BS, et al. African Journal of Traditional, Complementary and Alternative Medicine . 2017;14:105. doi: 10.21010/ajtcam.v14i3.11. 

Ref6- Potu BK, et al. Clinics . 2008;63:815. doi: 10.1590/S1807-59322008000600018.

Ref7- Ref- Bang JS, Oh DH, Choi HM, Sur BJ, Lim SJ, Kim JY, Yang HI, Yoo MC, Hahm DH, Kim KS. Anti-inflammatory and antiarthritic effects of piperine in human interleukin 1beta-stimulated fibroblast-like synoviocytes and in rat arthritis models. Arthritis Res Ther. 2009;11(2):R49. doi: 10.1186/ar2662.

Ref8- Mor A, Abramson SB, Pillinger MH. The fibroblast-like synovial cell in rheumatoid arthritis: a key player in inflammation and joint destruction. Clin Immunol. 2005;115:118–128. doi: 10.1016/j.clim.2004.12.009.

Ref9- Reginster JY, Neuprez A, Lecart MP, Sarlet N, Bruyere O. Role of glucosamine in the treatment for osteoarthritis. Rheumatol Int. 2012 Oct;32(10):2959-67. doi: 10.1007/s00296-012-2416-2. Ref10- Julio A. Martinez-Silvestrini ,Prescribing Medications for Pain and Inflammation, 15 May 2009,DOI10.1016/b978-141602443-9.50018-0 

Ref11- Zeng, C., Li, J., Yang, Y., & Wei, J. (2015). Efficacy of collagen peptide supplementation in improving symptoms of osteoarthritis. International Journal of Rheumatic Diseases, 18(4), 373-379. doi:10.1111/1756-185X.12555

Ref12- Kim, L. S., Lee, J. W., & Lee, B. W. (2011). Effect of methylsulfonylmethane (MSM) on osteoarthritis of the knee: A randomized, double-blind, placebo-controlled trial. Clinical Rheumatology, 30(5), 809-815. doi:10.1007/s10067-011-1730-4